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Precautions
As previously seen in the animal studies,1′ 5- 6 intravenous clonidine produced a brief hypertensive response in these patients; a long-lasting deCLONIDINEI crease in blood pressure followed, During the hypotensive response there was a decrease in cardiac output while the total peripheral clonidine weaning off clonidine bioavailability clonidine to help sleep clonidine structure maximum resistance did not change .
Heart rate decreased by 5 to 7% and clonidine stroke volume by 8 to 1085 .
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