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  • August 15, 2020 at 8:24 pm #40852
    vangoga
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    If renal impairment complicates the picture for tetracycline-sensitive organisms, the only reasonable drug in tetracycline this category would appear to be doxycycline .
    In our investigation of humans with severe renal disease, we found tetracycline low urine concentrations of doxycycline but remarkably effective renal tissue levels of the drug,12 the latter probably reflecting the drug’s previously noted lipophilicity .

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