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In the perioperative setting, continue clonidine up to 4 hr prior to surgery and resume clonidine as soon as possible thereafter .
clonidine Do not interrupt transdermal clonidine during surgery .
PO: Administer last dose of the day clonidine at bedtime .
May be taken without regard for Swallow extended-release tablets clonidine whole; do not crush, break, or chew .
Transdermal: Transdermal system should be applied once every clonidine 7 days .
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